Light-induced activation of a specific type-5 metabotropic glutamate receptor antagonist in the ventrobasal thalamus causes analgesia in a mouse model of breakthrough cancer pain

HIGHLIGHTS

• who: Serena Notartomaso et al. from the Department of Physiology and Pharmacology, Sapienza University, Rome, Italy have published the Article: Light-Induced Activation of a Specific Type-5 Metabotropic Glutamate Receptor Antagonist in the Ventrobasal Thalamus Causes Analgesia in a Mouse Model of Breakthrough Cancer Pain, in the Journal: (JOURNAL)
• what: Prodrugs activated by light in specific brain regions may offer a new strategy for the treatment of severe, sporadic, pain, which is difficult to manage with conventional analgesic agents.
• how: The authors examined whether light-activated JF-NP-26 in two regions . . .
  

   

  

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