Coenzyme a-dependent tricarboxylic acid cycle enzymes are decreased in alzheimer`s disease consistent with cerebral pantothenate deficiency

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  • who: Garth J. S. Cooper from the Karolinska Institutet (KI), Sweden University of Perugia, Italy have published the research work: Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer`s Disease Consistent With Cerebral Pantothenate Deficiency, in the Journal: (JOURNAL)
  • what: The authors aimed to test the role of cerebral pantothenic acid deficiency in the pathogenesis of AD by measuring the levels of enzymes and enzyme complexes implicated in the TCA cycle, to assess the potential roles of altered energyproducing pathways in the pathogenesis of AD. The authors report measurements of 33 proteins . . .

     

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