Alternatively spliced exon regulates context-dependent mef2d higher-order assembly during myogenesis

HIGHLIGHTS

  • who: Mu00f3nika Gu00f6nczi from the (UNIVERSITY) have published the paper: Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis, in the Journal: (JOURNAL) of 10/03/2022
  • what: Based on these results the authors reason that the alternatively spliced u03b2-domain serves as an interaction element for Mef2D higher-order assembly, which is required for transcription potentiation and differentiation. By introducing mutations into the u03b2-domain and its flanking region based on FuzDrop predictions, the authors aimed at modulating Mef2D higher-order assembly.
  • how: The authors have found a negative . . .

     

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