HIGHLIGHTS
- who: Yanjun Zhang from the Provincial Key LaboratoryZhejiang University, Hangzhou, Zhejiang, China have published the research work: SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- how: For this screening the authors selected known H3K36 methyltransferases major histone methyltransferases that contain SET domains and are responsible for depositing histone marks at promoters PRDM family proteins which contain SET domains SMYD family proteins which are reported to be responsible for H3K4me3 deposition at promoters and ZMYND family proteins which are potential H3K36 methylation readers. Because H3K36me3 was located at . . .
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