HIGHLIGHTS
- who: ufeffYuningufeff ufeffChenufeff and collaborators from the Yale University, United States have published the article: Genetic engineering strategies to enhance antitumor reactivity and reduce alloreactivity for allogeneic cell-based cancer therapy, in the Journal: (JOURNAL)
- future: Studies are needed to analyze how the occurrence of antigen spreading could enhance the efficiency of immune checkpoint inhibition therapy. From the perspective of the HvG effect studies have indicated that ablating HLAs including B2M HLA-DR and CIITA could successfully augment graft success rate. Though further research is required to understand the functions of LAG-3 geneediting provides . . .
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