HIGHLIGHTS
- who: Amber K. Virdi et al. from the Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA have published the article: An Efficient Humanized Mouse Model for Oral Anti-Retroviral Administration, in the Journal: Cells 2023, 12, 1034. of /2023/
- what: The authors demonstrate an effective mouse model utilizing immune-compromised mice reconstituted with infected human peripheral blood mononuclear cell (PBMCs). Within this study, the authors have established a physiologically relevant and cost-effective humanized mouse model that can be used to assess the HIV infection and oral ARV administration. Though . . .
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