HIGHLIGHTS
- who: . et al. from the National University of Galway, Germany have published the research work: Perinatal derivatives: How to best validate their immunomodulatory functions, in the Journal: (JOURNAL)
- what: Macrophage activities, the authors provide various considerations for setting up appropriate functional assays for evaluating the therapeutic potency of MSC and PnD products.
SUMMARY
Contrary to the initial expectations, upon administration in_vivo, allogenic MSCs are not acutely destroyed by the immune system, but display a strong modulating function on various immune cells by suppressing their pro-inflammatory activities and inducing their regulatory . . .
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