Loss of gpr40 in ldl receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis

HIGHLIGHTS

• who: Zhongyang Lu and collaborators from the Editor:, Tokyo University of have published the Article: Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis, in the Journal: PLOS ONE of 21/03/2022
• what: Taken together this study demonstrated for the first time that loss of GPR40 in LDLR-deficient mice exacerbated HFD-induced hyperlipidemia hepatic steatosis inflammation and fibrosis potentially through a CD36-dependent mechanism Competing interests: No authors have competing interests. The authors generated GPR40 and LDLR double KO (DKO) mice and studied the role . . .
  

   

  

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