Urolithin a targets the akt/wnk1 axis to induce autophagy and exert anti-tumor effects in cholangiocarcinoma

HIGHLIGHTS

• who: Hidenori Sahashi from the JSS Academy of Higher Education and Research, India University, Turkey have published the article: Urolithin A targets the AKT/WNK1 axis to induce autophagy and exert anti-tumor effects in cholangiocarcinoma, in the Journal: (JOURNAL)
• what: The authors aimed to investigate the antitumor effects of UA in CCA and elucidate its mechanism, including autophagy. The authors demonstrated that UA showed antitumor IGF-1, known as the AKT-WNK1 signal activator, demonstrated that UA downregulated phospho-WNK1 levels even in HuCCT-1 cells treated with IGF-1.
• how: To . . .
  

   

  

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