HIGHLIGHTS
- who: Federica De Lorenzi from the Department of Nanomedicine and Theranostics, Institute Aachen University Clinic, Aachen, Germany have published the research work: Profiling target engagement and cellular uptake of cRGD-decorated clinical-stage core-crosslinked polymeric micelles, in the Journal: (JOURNAL)
- what: The authors decorated clinicalstage CCPM with the u03b1vu03b23 integrin-targeted cyclic arginine-glycine-aspartic acid (cRGD) peptide which is one of the most well-known active targeting ligands evaluated preclinically and clinically. The authors show that incubation time and temperature as well as the expression levels of u03b1vu03b23 integrin by target cells positively . . .
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