Cancer cell-derived pdgfb stimulates mtorc1 activation in renal carcinoma

HIGHLIGHTS

• who: Asmaa Y. Abuhamad et al. from the Sciences, Universiti Putra Malaysia, Serdang, Malaysia Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland have published the Article: Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma, in the Journal: (JOURNAL)
• what: The authors utilized the KLF6- and PDGFB-engineered ccRCC cells to investigate whether ccRCC cells secrete PDGFB extracellularly and are able to stimulate mTORC1 signalling pathway activity.
• how: The authors investigated whether ccRCC cells are able to secrete into the extracellular milieu and stimulate signalling activity. The authors found . . .
  

   

  

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