A new in silico antibody similarity measure both identifies large sets of epitope binders with distinct cdrs and accurately predicts off-target reactivity

HIGHLIGHTS

• who: Astrid Musnier and collaborators from the MAbSilico, Impasse du Palais, Tours, France have published the research work: A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity, in the Journal: (JOURNAL) of 15/04/2015
• what: The authors aim to develop in silico tools to help and accelerate Ab discovery and characterization, starting as soon as the sequence is known. For further studies, the authors focused on two of these Ab fragments: 3SM5 and 4N1H, which have the best similarity scores . . .
  

   

  

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