Inorganic nanomaterials versus polymer-based nanoparticles for overcoming neurodegeneration

HIGHLIGHTS

SUMMARY

    Currently, available treatments based acetylcholinesterase inhibitors in_vitro and/or in_vivo studies have reported the potential use of natural compounds (donepezil, rivastigmine, and galantamine), which act at the synaptic level and are as therapeutic agents such as sesamol, curcumin, A, phosphatidic resveratrol, highly unstable in blood. Other substances that have been tested in in_vitro and/or in_vivo studies for PD include N-3,4-bis(pivaloyloxy)-dopamine (BPD), glial cell line-derived neurotrophic factor (GDNF), basic fibroblast growth factor (bFGF), coenzyme Q10 (CoQ10), resveratrol, and apomorphine andropirinole. There is no approved therapy able to modify . . .

     

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