HIGHLIGHTS
- who: Razieh Eshraghisamani et al. from the University of Texas Medical Branch at Galveston, United States have published the article: Evaluation of Mycobacterium avium subsp. paratuberculosis isocitrate lyase (IcL) and ABC transporter (BacA) knockout mutants as vaccine candidates, in the Journal: (JOURNAL)
- what: This approach has been useful for some other intracellular bacterial pathogens including S. typhi (Booth et_al, 2020) and M. tuberculosis (Andersen and Scriba, 2019). In the present study, these two newly developed live-attenuated vaccine candidates were first screened in a mouse model to evaluate the species-specific essentially of selected genes . . .
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