Synthesis of bio-inspired 1,3-diarylpropene derivatives via heck cross-coupling and cytotoxic evaluation on breast cancer cells

HIGHLIGHTS

• who: Aik Sian Tan and collaborators from the School of, Universiti Sains Malaysia, Gelugor, Penang, Malaysia have published the research: Synthesis of Bio-Inspired 1,3-Diarylpropene Derivatives via Heck Cross-Coupling and Cytotoxic Evaluation on Breast Cancer Cells, in the Journal: Molecules 2022, 27, 5373. of 23/08/2022
• what: A series of new bio-inspired (E)-1,3-diarylpropene derivatives were synthesised using palladium-catalysed Heck cross-coupling reactions of 2-amidoiodobenzene derivatives with either estragole or eugenol, in 36-91% yields.
• how: In this study a normal breast cell line . . .
  

   

  

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