The human scn9ar185h point mutation induces pain hypersensitivity and spontaneous pain in mice

HIGHLIGHTS

  • who: Yaping Xue1 and colleagues from the Centre National de la Recherche Scientifique (CNRS), Institut de la Santu00e9 de la Recherche Mu00e9dicale (INSERM), Institut France, Centre National de la Recherche Scientifique (CNRS) UMR, Universitu00e9 de, France University College London have published the research: The Human SCN9AR185H Point Mutation Induces Pain Hypersensitivity and Spontaneous Pain in Mice, in the Journal: (JOURNAL)
  • what: Altogether the authors provide genetic evidence for the fact that the SCN9A-encoded Nav1.7 channel plays a crucial role in pain behavior.
  • how: Before injecting sgRNAs into eggs the efficiency of . . .

     

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