Elasticity of podosome actin networks produces nanonewton protrusive forces

HIGHLIGHTS

  • who: Jonathan Schneider and collaborators from the Max Planck Institute have published the research: Elasticity of podosome actin networks produces nanonewton protrusive forces, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that the protrusive forces generated by podosomes cannot be explained by the sum of the actin polymerization forces at the core membrane but by the storage of elastic energy into the dense network of bent actin filaments.
  • how: The results showed that mechanical energy accumulates inside the podosome core through bending of the dense network of actin filaments (Figs . . .

     

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