Comparative expression profiling reveals molecular markers involved in the progression of cutaneous melanoma towards metastasis

HIGHLIGHTS

  • who: Andreea D. Lazu0103r and collaborators from the Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania have published the research work: Comparative Expression Profiling Reveals Molecular Markers Involved in the Progression of Cutaneous Melanoma towards Metastasis, in the Journal: (JOURNAL)
  • what: The authors found several MMP molecules to be significantly overexpressed in metastatic cell lines compared to primary tumor cells (e_g, MMP1, MMP2, MMP3, MMP9), with a dramatic increase registered for MMP2.
  • how: The results showed that most of the evaluated molecules were down-regulated in metastatic melanoma cells commiRNA . . .

     

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