HIGHLIGHTS
- who: Kristin Wowk from the University of of Medicine, Chapel Hill, NC, USA have published the Article: Cite as: A. Schu00e4fer et al ., Sci. Transl. Med. 10.1126/scitranslmed.abm3410 (2022), in the Journal: (JOURNAL) of 22/03/2022
- what: The authors demonstrate the in vitro antiviral activity and in vivo therapeutic efficacy of GS-621763 an orally bioavailable prodrug of GS-441524 the parent nucleoside of remdesivir which targets the highly conserved virus RNA-dependent RNA polymerase. The authors show that GS621763, a prodrug that improves the oral delivery of parent nucleoside GS-441524 . . .
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