Wiskott-aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting il-2 induction

HIGHLIGHTS

• who: . and collaborators from the University of Siena, Italy have published the article: Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction, in the Journal: (JOURNAL)
• what: The authors explored the signalling pathways that mediate TCR-induced DGKa inhibition through the SAP adaptor protein. The authors focused the attention on WASp as this protein is known to interact with molecules downstream to SAP such as CDC42 and NCK-1 and there are some similarities in the XLP-1 and WAS disease phenotypes .
• how: Data are analysed with FCS . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.