The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain

HIGHLIGHTS

  • who: Dexu Kong from the Department of Anesthesiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China have published the Article: The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain, in the Journal: (JOURNAL)
  • what: The authors used retrograde labeling and projection-specific chemogenetic manipulation of the LCRVM circuit in mice to determine the precise role of the LC-RVM circuit in stress-induced effects on visceral pain. Successful induction of the model was confirmed by increased stool consistency, appearance of blood in the stool, a marked reduction . . .

     

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