HIGHLIGHTS
- who: A Yeong Lee from the University of Lu00fcbeck, Germany have published the research: Understanding CD4+ T cells in autoimmune bullous diseases, in the Journal: (JOURNAL)
- what: This study demonstrated that ICOS+ Tfh cells are required for the induction of the PV phenotype . This study showed that OX40-OX40L signaling is important in disrupting Treg-dependent peripheral tolerance of DSG3-sepcific TCR-transgenic CD4+ T_cells .
- how: This review describes current views on the role of CD4 + T_cells in AIBDs with a focus on pemphigus and bullous pemphigoid (BP). frontiersin.org 10.3389/fimmu . . .
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