Traf6 suppresses the development of pulmonary fibrosis by attenuating the activation of fibroblasts

HIGHLIGHTS

  • who: Jiali Min and colleagues from the Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China have published the research: TRAF6 Suppresses the Development of Pulmonary Fibrosis by Attenuating the Activation of Fibroblasts, in the Journal: (JOURNAL)
  • what: The work provides insight into the regulatory role of TRAF6 in Wnt3a expression in fibroblasts.
  • how: PCR results showed that Traf6 mRNA expression was comparable in lung fibroblasts from vehicle- and BLM-challenged mice . These data indicated that the decreased protein expression of TRAF6 in lung fibroblasts during PF . . .

     

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