scn1a channelopathies: navigating from genotype to neural circuit dysfunction

HIGHLIGHTS

  • who: ufeffAlexanderufeff ufeffBrysonufeff from the University of Buenos Aires, Argentina have published the article: ufeffSCN1Aufeff channelopathies: Navigating from genotype to neural circuit dysfunction, in the Journal: (JOURNAL)
  • what: The authors provide a brief overview of the genetic basis and clinical features of SCN1A channelopathies, and then consider their impact upon neuronal and neural circuit function.
  • future: It remains unclear precisely how these findings relate to ictogenesis and further work is required to dissect the contribution of interneuron subtypes to ictal network activity.

SUMMARY

    SCN1A encodes the alpha subunit of . . .

     

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