Low-dose il-2 reduces il-21+ t cell frequency and induces anti-inflammatory gene expression in type 1 diabetes

HIGHLIGHTS

  • who: Jia-Yuan Zhang from the (UNIVERSITY) have published the paper: Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes, in the Journal: (JOURNAL) of 10/04/2022
  • what: The authors examine the effects of interval administration of low-dose recombinant IL-2 (iLD-IL-2) in type 1 diabetes using high-resolution single-cell multiomics and flow cytometry on longitudinally-collected peripheral blood samples. Although the authors show that iLD-IL-2 can induce this signature, it is certainly not the only responsible . . .

     

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