Coxsackievirus b3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells

HIGHLIGHTS

  • who: Julia Mamana from the Heidelberg University, Germany have published the research: Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells, in the Journal: (JOURNAL)
  • what: The work investigates the ability for clinically relevant CVB3 to access the brain.
  • future: Elucidating mechanisms by which other enteroviruses such as echoviruses can impact iBECs may provide valuable insights in future studies. In theory shedding of virus into the brain from the infected BBB is likely how at least initial brain infection occurs however future studies will assess if gradual . . .

     

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