The iqgap scaffolds: critical nodes bridging receptor activation to cellular signaling

HIGHLIGHTS

• who: The IQGAP scaffolds Critical and collaborators from the of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA have published the article: The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling, in the Journal: (JOURNAL) of 20/04/2023
• what: The multidomain composition of IQGAP1 enables scaffolding of multiprotein complexes, comprising both receptors and signaling proteins.

SUMMARY

Activates the transcription factors STAT1/3 Chen et_al, 2022 MAPK B-Raf IQ Ren et_al, 2007 C-Raf IQ and RGCT Sbroggiò et_al, 2011 MEK1 IQ MEK2 ERK1 Facilitates . . .

 



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