Release systems based on self-assembling rada16-i hydrogels with a signal sequence which improves wound healing processes

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SUMMARY

    The plasma was aliquoted and incubated with the desired compounds for 24 h at 37 °C, at final concentrations of 5.83 µM for RADA, 3.12 µM for RADAIM, 3.76 µM for RADA-KGHK and 3.52 µM for RADA-GHK using a ratio of 4 parts of plasma to 1 part peptide. Accelerated wound healing compared to RADA16-I was observed following application of the RADA-GHK and RADA-KGHK peptide hybrids. On day 7 of the experiment, the groups treated with the RADA-GHK and the RADA-KGHK showed more . . .

     

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