HIGHLIGHTS
- who: Anna-Polina Shurygina and colleagues from the Smorodintsev Research Institute of Influenza of the Ministry of Health of the Russian Federation have published the research: Preclinical Evaluation of TB/FLU-04Lu2014An Intranasal Influenza Vector-Based Boost Vaccine against Tuberculosis, in the Journal: (JOURNAL)
- what: The authors show the results of the preclinical evaluation of safety, immunogenicity, and protective efficacy of TB/FLU-04L-a replication-deficient intranasal influenza vector vaccine, expressing two Mtb antigens, ESAT-6 and Ag85A. The evidence showed that the main reason for the immune system failing to eliminate Mtb during . . .
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