Estrogen receptor- targeting: protacs, snipers, peptide-protacs, antibody conjugated protacs and snipers

HIGHLIGHTS

  • who: Arvind Negi and colleagues from the Department of Bioproduct and Biosystems, Aalto University, Espoo, Finland have published the research work: Estrogen Receptor- Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs, in the Journal: Pharmaceutics 2022, 2523 of /2022/
  • what: The present review provides a broad summary and discusses the highlights of discoveries, SAR studies, and binding interactions of various degraders of ERs reported to date. The approach showcases an example of precise spatiotemporal resolution has been exploited as chemical biology tools and in phototherapies , where a specific wavelength of light activates the . . .

     

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