Small vault rna1-2 modulates expression of cell membrane proteins through nascent rna silencing

HIGHLIGHTS

  • who: Adele Alagia and colleagues from the Sir William Dunn School of Pathology, University of Oxford, Oxford, UK Biomedical Research Centre, Oxford, UK have published the Article: Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing, in the Journal: (JOURNAL)
  • what: Although the authors described the fundamental mechanism of NRS, the understanding of the molecular and functional details remains limited. The authors show that vtRNA1-2 molecule can be actively processed by Dicer into svtRNA1-2 fragments, associate with Ago2, and localise predominantly in the nucleus. The authors show that . . .

     

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