HIGHLIGHTS
SUMMARY
Organoids from embryonic pancreas or human pluripotent stem_cells To decipher the pathophysiological process of pancreas development and diseases better, the emergence of the organoid culture provides another alternative to disentangle the sophisticated mechanisms. Previous study has indicated that cells that express SRY-box transcription factor 9 (SOX9) in the mouse fetal pancreas have the capacity to regenerate endocrine and acinar cells. Diverse studies make use of different cell markers, which represent pluripotent stem_cells (PSCs), to isolate cells that can differentiate into organoids from the pancreas and their cultivation methods are also slightly different. No . . .
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