In-silico eeg biomarkers of reduced inhibition in human cortical microcircuits in depression

HIGHLIGHTS

  • who: Frank Mazza and colleagues from the Department of Physiology, University of, Canada, Krembil Brain Institute, University Healthy have published the article: In-silico EEG biomarkers of reduced inhibition in human cortical microcircuits in depression, in the Journal: (JOURNAL) of April/10,/2023
  • how: To overcome these limitations the authors simulated resting-state activity and EEG using detailed models of human cortical microcircuits with normal (healthy) or reduced SST interneuron inhibition (depression) and found that depression microcircuits exhibited increased theta alpha and low beta power (4-16 Hz). The authors compared simulated EEG in healthy . . .

     

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