HIGHLIGHTS
SUMMARY
International standard for biomedical research: "All proposals out to conduct research involving human subjects must be submitted for review of their scientific merit and ethical acceptability to one or more scientific review and Ethical Review Committees". This set the requirement for involving human subjects in research which established the need for the creation of Institutional Review Boards (IRBs) known also as Research Ethics Committees (RECs) and provided them with the authority and the responsibility for approving or disapproving proposals to conduct research. Ultimately, RECs have the authority to approve, reject, pause or even stop . . .
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