Flexr: automated multi-conformer model building using electron-density map sampling

HIGHLIGHTS

  • who: FLEXR. et al. from the Department of Chemical Biology and Therapeutics, St Jude Children`s Research Hospital, Memphis, TN, USA have published the research work: FLEXR: automated multi-conformer model building using electron-density map sampling, in the Journal: (JOURNAL)
  • what: The overall goal of this project was to produce a tool that automatically incorporates weakly populated, high-energy alternative side-chain conformations from Ringer measurements into models.
  • how: The authors identified two instances where FLEXR finds hidden side-chain conformations that are missing in the deposited and qFit models and would . . .

     

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