Nod-like receptor nlrc5 promotes neuroinflammation and inhibits neuronal survival in parkinson’s disease models

HIGHLIGHTS

• who: Zhaolin Liu from the All experimental protocols were approved by the Institutional Animal Care and Use Committee of Fudan University, Shanghai Medical CollegeNlrc5-/- (knockout, KO) mice and littermate control (wild-type, WT) mice weighing between , and , g were obtained from Shanghai Model Organisms Center, Inc. (Shanghai, China) and were generated with the C BL/, strain as previously described [37]. KO and WT mice were maintained under a, h light-dark cycle in temperature-controlled rooms (18, u00b0C), with libitum access to food and water. For the acute, methyl-4-phenyl-1, , tetrahydropyridine (MPTP)-induced mouse model . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.