HIGHLIGHTS
- who: Martyna Tomaszewicz et al. from the University of Florida, Jupiter, United States have published the Article: T regulatory cells metabolism: The influence on functional properties and treatment potential, in the Journal: (JOURNAL)
- how: Another research group carried out an experiment on mice models to check the interplay between FoxP3 and HIF-1a and the results showed that HIF-1a enhances FoxP3 ubiquitination and degradation . A phase 2 single-centre randomized double-blind placebocontrolled study was carried out and results showed that Rapamycin treatment reduced insulin requirements in longlasting Type 1 Diabetic patients .
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