Histone deacetylase inhibitors restore cancer cell sensitivity towards t lymphocytes mediated cytotoxicity in pancreatic cancer

HIGHLIGHTS

  • who: Chin-King Looi and collaborators from the School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia have published the Article: Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer, in the Journal: (JOURNAL) of 27/Oct/2019
  • what: Through the in silico and in vitro studies the authors demonstrate the novel role of HDAC inhibition in restoring CTL resistance and that combinations of HDACi with CTL may represent a promising therapeutic strategy 4.0/). __NEWPAGE__Cancers 2022 14 3709 2 of 22 warranting its further detailed molecular mechanistic . . .

     

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