Scmomat jointly performs single cell mosaic integration and multi-modal bio-marker detection

HIGHLIGHTS

  • who: Ziqi Zhang from the (UNIVERSITY) have published the research work: scMoMaT jointly performs single cell mosaic integration and multi-modal bio-marker detection, in the Journal: (JOURNAL) of 13/01/2023
  • what: The authors propose scMoMaT, a method that is able to integrate single cell multi-omics data under the mosaic integration scenario using matrix tri-factorization. Specifically, the authors show that integrated cell embedding combined with learned bio-markers lead to cell type annotations of higher quality or resolution compared to their original annotations. The authors compare the performance of scMoMaT with state . . .

     

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