Polygenic risk score-based phenome-wide association study identifies novel associations for tourette syndrome

HIGHLIGHTS

  • who: Pritesh Jain from the (UNIVERSITY) have published the research work: Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome, in the Journal: (JOURNAL) of 23/01/2023
  • how: To account for multiple testing the authors used a Bonferroni threshold of p and amplt 2.3 u00d7 10-5 (0.05/2242) for the results of the main analyses. The authors conducted a PRS-based PheWAS analysis to understand and identify associations between genetic liability for Tourette syndrome and 2242 phenotypes available in the UK Biobank dataset. The results the . . .

     

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