Case report: dramatic response to pralsetinib in an elderly patient with advanced ret-fusion positive papillary thyroid carcinoma

HIGHLIGHTS

  • who: Margherita Nannini from the Uniformed Services University of the Health Sciences, United States have published the paper: Case report: Dramatic response to pralsetinib in an elderly patient with advanced RET-fusion positive papillary thyroid carcinoma, in the Journal: (JOURNAL)
  • what: The authors report the case of an elderly patient with advanced papillary thyroid carcinoma (PTC) harboring RET::CCDC6 fusion with four co-occurring mutations involving PI3KCA, TP53, and hTERT mutations, with an impressive clinical and radiologic response to pralsetinib under a compassionate use program (AG43388 - Roche). The study was approved by the local Ethic . . .

     

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