Differential regulation of allergic airway inflammation by acetylcholine

HIGHLIGHTS

  • who: Luke B. Roberts from the London, London, United Kingdom, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom have published the Article: Differential Regulation of Allergic Airway Inflammation by Acetylcholine, in the Journal: (JOURNAL)
  • what: The authors demonstrate that RoraCre+ChatLoxP mice, in which ILC2s cannot synthesize ACh, show enhanced neutrophilia in the airways following acute exposure to an allergenic extract of A. alternata.

SUMMARY

    Acetylcholine (ACh) is best known as a neurotransmitter, but in recent years, it has been increasingly implicated as an important signaling molecule . . .

     

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