HIGHLIGHTS
- who: Ankur Kumar from the University of Washington, United States have published the paper: Drugs to limit Zika virus infection and implication for maternal-fetal health, in the Journal: (JOURNAL)
SUMMARY
ZIKV replicates in the host by overcoming the interferon (IFN)mediated host immune_response that induces the degradation of the interferon-regulated transcriptional activator STAT2, leading to impairment of IFN induction and downstream IFN stimulated genes. ZIKV-induced apoptosis may also be due to the activation of the immune_response, leading to the upregulation of viral response genes associated with toll-like receptor (TLR . . .
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