HIGHLIGHTS
- who: Zheng Jian from the The University of Hong Kong, Hong Kong SAR, China have published the research: Potential roles of PIWI-interacting RNAs in lung cancer, in the Journal: (JOURNAL)
- future: More effective diagnostic and therapeutic approaches are still required.
SUMMARY
Similar to silencing mechanism of miRNA, the piRNA/PIWI complex interacts with target RNA through efficient piRNA: RNA binding is formed by either a strict base_pairing within 2~11 nt at the 5` end of the piRNA (perfect pairing) or a less strict base_pairing within 12~21 nt (imperfect . . .
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