HIGHLIGHTS
SUMMARY
Alzheimer`s disease (AD) and diabetes_mellitus (DM) are among the most common diseases associated with aging. In 2005, Suzanne de la Monte introduced the term "type 3 diabetes_mellitus" (T3DM) in reference to AD. The term T3DM accurately reflects the fact that AD represents a form of diabetes that selectively involves the brain and has molecular and biochemical features that overlap with both type 1 and type 2 diabetes_mellitus (T1DM and T2DM, respectively). Pleiotropy studies designed to detect cross-phenotype genetic associations between cardiovascular risk factors and AD have demonstrated that the genetic enrichment in . . .
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