HIGHLIGHTS
- who: from the (UNIVERSITY) have published the article: Supplemental Materials and Methods CAR construct and CAR T-cell manufacturing CD7 CAR T-cells were manufactured with T cells, obtained through leukapheresis, and were, in the Journal: (JOURNAL)
SUMMARY
Supplemental Materials and Methods CAR construct and CAR T-cell manufacturing CD7 CAR T-cells were manufactured with T_cells, obtained through leukapheresis, and were completed in 6-7 days. To minimize CD7 CAR-T_cell-mediated fratricide, the authors designed a CD7- targeting CAR construct using IntraBlock technology, which prevents CD7 cell surface expression on CAR . . .
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