The generation, activation, and polarization of monocyte-derived macrophages in human malignancies

HIGHLIGHTS

  • who: Paul Chaintreuil from the Hospital for Special Surgery, United States University of Granada, Spain have published the paper: The generation, activation, and polarization of monocyte-derived macrophages in human malignancies, in the Journal: (JOURNAL)
  • how: A phase I study was conducted in patients with pigmented villonodular synovitis (SVN or diffuse-type giant cell tumor (Dt-GCT)) a rare type of tumor. This study was motivated by the fact that these agonists are used in clinical studies individually.

SUMMARY

    When CD40L, expressed on the surface of activated T_cells, binds to the . . .

     

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