HIGHLIGHTS
SUMMARY
Human-induced pluripotent stem_cells (hiPSCs) cells have the proliferative potential and ability to differentiate into numerous cell types. The authors have previously generated vascular wall-derived reparative cells called endothelial colony-forming cells (ECFCs) from iPSCs derived from well-characterized, healthy, and diabetic individuals. The studies showed that these human iPSCs incorporate into blood vessels when implanted subcutaneously into immune compromised mice. These cells, of either diabetic or nondiabetic origin, when injected into the vitreous of diabetic mice with retinal damage, are incorporated Biol. Forum 2023, 21, 33 2 of 2 into retinal blood . . .
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