Specific dna binding of archaeal histones hmfa and hmfb

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  • who: ufeffAmanda M.ufeff ufeffErkelensufeff from the The University of Newcastle, Australia have published the paper: Specific DNA binding of archaeal histones HMfA and HMfB, in the Journal: (JOURNAL)
  • what: The authors show that HMfA and HMfB modestly compact Clone20 DNA by forming a tetrameric complex before hypernucleosome formation and that histone derivatives with impaired stacking interactions are still able to recognize the Clone20 sequence. The authors propose a model where the first step is binding of a dimer to the DNA, directly followed by recruitment of the second dimer to form a stable tetrameric . . .

     

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