HIGHLIGHTS
- who: Ashraf Mahmud from the Oregon Health and Science University, United States have published the paper: Awakening the dormant: Role of axonal guidance cues in stress-induced reorganization of the adult prefrontal cortex leading to depression-like behavior, in the Journal: (JOURNAL)
- what: The authors propose that chronic stress-induced changes in axonal guidance cue function trigger the reorganization of local PFC circuitry increasing incidence of behavioral abnormalities in rodents and the onset and severity of depression in humans. The authors show cartoon representations of the domain arrangements of the classical guidance cue families (Netrin . . .
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